Dementia Japan 31:242-250, 2017

Cerebrospinal fluid physiology revisited─MRI Time-SLIP method─

Shinya Yamada

Toshiba Rinkan Hospital, Neurosurgery, Hydrocephalus & Cerebrospinal Fluid Center

Cerebrospinal fluid (CSF) dynamics has been directly visualized by newly developed Magnetic Resonance Imaging technique called time spin labeling inversion pulse (Time-SLIP).  Time-SLIP revealed different aspect of CSF dynamic than it has been believed for a hundred year.  These observations lead us to revisit Cerebrospinal fluid physiology.

Address correspondence to Dr. Shinya Yamada, Toshiba Rinkan Hospital, Neurosurgery, Hydrocephalus & Cerebrospinal Fluid Center(7-9-1 Kamitsuruma, Minami-ku, Sagamihara, Kanagawa 252-0385, Japan)