Dementia Japan 29: 9-25, 2015

Life style and dementia:diet and exercise in the prevention of dementia

Michio Hashimoto

Department of Environmental Physiology, Shimane University Faculty of Medicine

    The prevention of dementia is a growing public health concern.  Epidemiological data indicate a protective role of certain micronutrients (the anti-oxidant vitamins C and E, flavonoids, ω-3 fatty acids, vitamin D) and exercise in the age-related cognitive decline and dementia.  However, many of the results obtained by interventions tested in randomized control trials (RCTs) are conflicting with observational evidence.  This paper is outlined the relevance of cognitive function, micronutrients and exercise, and after that review the possibility of preventive effects of ω-3 fatty acids, especially docosahexaenoic acid, in the prevention of dementia.

Address correspondence to Dr. Michio Hashimoto, Department of Environmental Physiology, Shimane University Faculty of Medicine(89-1 Enyacho, Izumo-shi, Shimane 693-8501)