Clinical utility of Voxel-based Specific Regional analysis system for Alzheimer’s Disease (VSRAD[®])

Clinical utility of Voxel-based Specific Regional analysis system for Alzheimer’s Disease (VSRAD^®)

Hiroshi Matsuda

Department of Nuclear Medicine, Saitama Medical University International Medical Center

Neuroimaging has played an adjunct role of early and differential diagnosis of Alzheimer’s disease in routine practice. Of several neuroimaging modalities, MRI has been commonly used in Japan with the aid of a software program for statistical imaging analysis, Voxel-based Specific Regional analysis system for Alzheimer’s Disease (VSRAD^®). This fully-automated program can detect selective atrophy in medial temporal structures in Alzheimer’s disease with high accuracy. Moreover it is very useful for objective assessments of progressive morphological changes in longitudinal studies. The next version-up of this program is expected to raise diagnostic performance by introduction of new techniques for tissue segmentation and anatomic standardization.

Address correspondence to Dr. Hiroshi Matsuda, Department of Nuclear Medicine, Saitama Medical University International Medical Center (1397-1 Yamane, Hidaka, Saitama 350-1298, Japan)