Dementia Japan 20: 46-54, 2006

Similarities and differences between AD and VaD

Fukashi Udaka

Department of Neurology, Sumitomo Hospital

    Although AD and VaD are different disease entity, there are many similarities. Moreover issues are complicated because AD is often accompanied by CVD. In this point of view, discussion was made on these four issues; 1) clinical and pathological problems in AD with CVD, 2) atherosclerosis and AD, 3) microvascular lesions of AD as a neurodegenerative disease, and 4) propriety of the vascular hypothesis of AD. Dementia is thought to be a brain insufficiency caused by a single or multiple pathology, and we should keep the fact in mind in daily clinical practice.

Address correspondence to Dr. Fukashi Udaka, Department of Neurology, Sumitomo Hospital (5-3-20, Nakanoshima, Kita-ku, Osaka 530-0005, Japan)