Tohoku J. Exp. Med., 1977, 122 (1)

Immunohistochemical Demonstration of Somatostatin-Containing Cells in the Human, Dog and Rat Thyroids

YUKIO YAMADA, SEIKI ITO, YOHICHI MATSUBARA^* and SHIGERU KOBAYASHI^†

The First Department of Internal Medicine, ^*The First Department of Surgery and ^†The Third Department of Anatomy, Niigata University School of Medicine, Niigata

By an indirect immunofluorescence technique using the somatostatin antibody, somatostatincontaining cells were demonstrated to exist in the human, dog and rat thyroids. These cells were located predominantly in the interfollicular areas and more scatteringly in the follicular areas. The source of these somatostatin-containing cells was discussed.

Keywords ——somatostatin; thyroid; immunofluorescence technique; parafollicular cells

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Tohoku J. Exp. Med., 1977, 122, 87-92