Tohoku J. Exp. Med., 2015 November, 237(3)

Cycling Exercise with Electrical Stimulation of Antagonist Muscles Increases Plasma Growth Hormone and IL-6

MASAYUKI OMOTO,¹ HIROO MATSUSE,¹ RYUKI HASHIDA,¹ YOSHIO TAKANO,² SHIN YAMADA,³ HIROSHI OHSHIMA,³ YOSHIHIKO TAGAWA⁴ and NAOTO SHIBA¹

¹Division of Rehabilitation, Kurume University Hospital, Kurume, Fukuoka, Japan
²Department of Physical Therapy School of Health Sciences, International University Health and Welfare, Okawa, Fukuoka, Japan
³Space Biomedical Research Group, Japan Aerospace Exploration Agency, Tsukuba, Ibaraki, Japan
⁴Department of Mechanical and Control Engineering, Kyushu Institute of Technology, Kitakyushu, Fukuoka, Japan

Performing aerobics and resistance exercise at exactly the same time has not been available although combining both types of exercise in one training program has been attempted. The hybrid training system (HTS) is a resistance exercise that combines voluntary concentric muscle contractions with electrically stimulated eccentric muscle contractions. We devised an exercise technique using HTS on a cycle ergometer (HCE). Growth hormone (GH) and lactate are indicators of adequate training intensity. Interleukin-6 (IL-6) reflects enhancing lipid metabolism. The purpose of this study was to show that HCE provides sufficient exercise to stimulate the secretion of GH, lactate and IL-6. We compared an HCE test with cycle ergometer alone (CE). Ten healthy male subjects performed HCE and CE tests for 30 minutes each. The workload of both tests was set the same at 40% of each subject's peak oxygen uptake. For HCE, 2-minute HTS and 1-minute rest intervals were repeated. GH, lactate, and IL-6 were evaluated before and immediately after exercise, and at 15, 30 and 60 minutes. GH and lactate increased immediately after HCE. Moreover, the degree of the increases in GH after HCE (0 and 15 minutes) was higher than that after CE. IL-6 increased after HCE at 30 min, and the rate of change was higher than for CE. These results showed that HCE was more efficient in stimulating acute increases in GH, lactate and IL-6 than CE at the same workload. We may be able to combine electrically stimulated resistance exercise with aerobic exercise using HCE.

keywords —— cycling exercise; electrical stimulation; growth hormone; interleukin-6; lactate

© 2015 Tohoku University Medical Press

===============================

Tohoku J. Exp. Med., 2015, 237, 209-217

Correspondence: Masayuki Omoto, M.D., Division of Rehabilitation, Kurume University Hospital, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan.

e-mail: omoto_masayuki@med.kurume-u.ac.jp