Tohoku J. Exp. Med., 2008, 214(1)

Short Bowel Syndrome: Amelioration of Diarrhea after Vagotomy and Pyloroplasty for Peptic Hemorrhage

MICHAEL SAFIOLEAS,¹ MICHAEL STAMATAKOS,¹ PANAGIOTIS SAFIOLEAS,¹ AHMAD DIAB,¹ EVRIDIKI KARANIKOLA¹ and CONSTANTINOS SAFIOLEAS¹

¹Second Department of Propaedeutic Surgery, Medical School, University of Athens, Laiko General Hospital, Athens, Greece

Acute mesenteric ischemia is a rare symptomatic manifestation of arteriosclerosis. Prognosis crucially depends on rapid diagnosis and surgical management to prevent or at least minimize the bowel infarction. The length of the small bowel is considered to be between 3 and 8 m, and a normal bowel function can be maintained even after resection of its one third. But loss of a major part (> 60%) can lead to malnutrition and death. However, patients, who survived an extended intestinal resection due to improved postoperative care (intensive care unit and parenteral nutrition), develop short bowel syndrome. This phenomenon is a medical problem, and several surgical techniques have been used to slow down intestinal transit time or to increase the area of absorption. All these procedures have controversial outcomes and are still on different experimental levels; namely, they cannot be recommended for routine use. In our report of a patient suffering from short bowel syndrome, vagotomy and pyloroplasty were performed to repair a sudden peptic hemorrhage. This operation cured bleeding peptic ulcer and also palliated the diarrhea, a main clinical manifestation of short bowel syndrome. In this study, our aim is to emphasize the favorable clinical outcome of vagotomy concerning a principal manifestation of short bowel syndrome, such as diarrhea. To the best of our knowledge, the present study is the first report showing the vagotomy as a possible procedure for the treatment of diarrhea, although this occurrence has no clear explanation. We also discuss the management of short bowel syndrome.

keywords —— short bowel syndrome; vagotomy; bowel infarction; mesenteric ischemia.

© 2008 Tohoku University Medical Press

===============================

Tohoku J. Exp. Med., 2008, 214, 7-10

Correspondence: Prof. Michael C. Safioleas, M.D., Ph.D., 7 Kyprou Ave, 15237, Filothei, Athens, Greece.

e-mail: stamatakosmih@yahoo.gr