Mood Change Tendency and Fasting Plasma Glucose Levels in a Japanese Female Population

Mood Change Tendency and Fasting Plasma Glucose Levels in a Japanese Female Population

KAZUHIKO KOTANI,^1,2 HISASHI SHIMOHIRO³ and NAOKI SAKANE²

¹Division of Health Administration and Promotion, Faculty of Medicine, Tottori University, Yonago, Japan
²Department of Preventive Medicine and Diabetes Education, Clinical Research Institute for Endocrine and Metabolic Disease, National Hospital Organization Kyoto Medical Center, Kyoto, Japan
³Division of Clinical Laboratory, Tottori University Hospital, Yonago, Japan

Internal stress can modify values in blood examinations such as glucose. Mood change releases us from the stress state, and the mood change tendency (MCT) may show individual differences. However, little is known about whether individual mood change tendencies in daily life affect fasting plasma glucose (FPG) levels. We investigated the effects of clinical characteristics including age, body mass index (BMI), smoking, alcohol habits and self-reported MCT (an answer to the inquiry on their daily MCT: good, average, or poor) on FPG values among 272 Japanese females (mean age 48.4 ± 9.3 years). Subjects with normal to impaired fasting glucose levels (less than 7.0 mmol/L) were included in this study. The mean FPG levels in subjects with good, average and poor MCT were 5.32 ± 0.48, 5.36 ± 0.50 and 5.58 ± 0.69 mmol/L, respectively. A significant difference was noted between subjects with good and poor MCT (p = 0.02). There was no significant difference in BMI levels among MCT-based groups. Pearson's rank correlation and multiple regression analysis, using FPG levels and other variables, demonstrated a significant relationship between FPG levels and MCT (p ≤ 0.01), along with age and BMI. These results suggest slight but significant effects of individual MCT on FPG, and that a consideration of MCT may occasionally be needed in the interpretation and management of FPG levels in the Japanese female population.

keywords —— glucose metabolism; mental stress; mood management; health administration; women

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Tohoku J. Exp. Med., 2007, 213, 369-372

Correspondence: Kazuhiko Kotani, M.D., Ph.D., Division of Health Administration and Promotion, Faculty of Medicine, Tottori University, 86 Nishi-cho, Yonago 683-8503, Japan.

e-mail: kakotani@grape.med.tottori-u.ac.jp