Tohoku J. Exp. Med., 2006, 210(2)

Case Report

Treatment of Idiopathic Gustatory Rhinorrhea by Resection of the Posterior Nasal Nerve

YAH YEE ANG, KENJI KAWANO, TATSUYA SAITO, MISATO KASAI and KATSUHISA IKEDA

Department of Otorhinolaryngology, Juntendo University School of Medicine, Tokyo, Japan

We herein describe a case of 44-year old female who presented with a chief complaint of gustatory rhinorrhea from childhood, in which gustatory stimuli caused bilateral excessive, watery nasal secretion. No abnormality of taste acuity was observed. This disorder was presumably caused by faulty regenerated parasympathetic nerve fibers reaching the nasal mucosa or possibly, by a congenital condition. Nasal pretreatment with an anti-cholinergic drug clinically blocked the positive sugar-induced rhinorrhea, thus indicating that the gustatory rhinitis in this case was produced by foods that stimulate muscarinic receptors sensitive to atropine (probably on submucosal nasal glands). Although this syndrome can be treated prophylactically by the use of topical atropine, the patient preferred to undergo radical therapy and a resection of the posterior nasal nerve was performed through the middle meatus under endoscopic control. The resection of the nerve on both sides resulted in an almost complete inhibition of the sugar-induced rhinorrhea without serious complications. Although this disease is not life-threatening, it is socially embarrassing and troublesome to patients and surgical therapy is one of the accepted modalities.

keywords —— gustatory rhinorrhea; posterior nasal nerve; nasal gland; muscarinic receptor

© 2006 Tohoku University Medical Press

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Tohoku J. Exp. Med., 2006, 210, 165-168

Correspondence: Katsuhisa Ikeda, Department of Otorhinolaryngology, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.

e-mail: ike@med.juntendo.ac.jp