Tohoku J. Exp. Med., 2002, 197 (1)

Clinical Value of Color Doppler Ultrasonography Measurements of Full-Term
Newborns with Perinatal Asphyxia and Hypoxic Ischemic Encephalopathy
in the First 12 Hours of Life and Long-Term Prognosis

ERCAN KIRIMI, OGUZ TUNCER, BULENT ATAS, MEHMET EMIN SAKARYA¹
and ABDULLAH CEYLAN

Departments of Pediatrics, and ¹Radiology, Yuzuncu Yil University Hospital, Van, Turkey

The cerebral blood flow velocities (CBFV) of infants with perinatal asphyxia and hypoxic ischemic encephalopathy (HIE) in the first 12 hours of their lives have been the chief focus of our concern in this study. Cerebral ischemia which can develop in the earlier hours of HIE, and the detection and diagnosis of this condition with color Doppler ultrasonography (cD-USG) will be put into discussion. Twenty-three full-term newborn infants who had perinatal asphyxia and HIE together with a control group constituting twenty full-term newborn infants who produced no problems, were included in our study. All of the infants underwent cD-USG in the postpartum period of the first 12 hours (mean 8.4 hours). Measurements being based upon peak systolic velocity (PSV), end diastolic velocity (EDV) and Pouecelout's resistive index (RI) in anterior and middle cerebral arteries were conducted. The infants, having been discharged from the unit they were followed up for mean 9.8 months in the outpatient clinic. PSV and EDV counts in the postpartum first 12 hours of 23 infants who were detected to have HIE were found to be significantly lower compared to the control group, whereas RI counts were found to be significantly higher (p

Keywords —— Doppler; neonatal; cerebral blood flow velocities

© 2002 Tohoku University Medical Press

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Tohoku J. Exp. Med., 2002, 197, 27-33

Address for reprints: Dr. Ercan Kirimi, Arastirma Hospital, Neonatal Unit, 65300 Van, Turkey.

e-mail: ercank@lycos.com