Comparison of the digital version B of L-Stroop test （dL-Stroop test B） with MMSE in validity and reliability for screening Mild Cognitive Impairment （MCI）

Woon Joo Lee^1）2）

^1）Osaka Lee Clinic
^2）Osaka University of Economics and Law

OBJECTIVES:This study aimed to compare a 2-minute dL-Stroop test B with the MMSE for screening MCI.
DESIGN:Validation study.
SETTINGS:A community clinic.
PARTICIPANTS:Ninety-three patients who met MCI clinical criteria supported by MoCA-J were compared with 66 patients with Alzheimer’s disease （AD） and 72 healthy normal controls （NC）.
MEASUREMENTS:The MoCA-J, dL-Stroop test B, and MMSE were conducted to participants to determine sensitivity and specificity for MCI and AD.
RESULTS:A negative correlation of ?0.674 was found between the dL-Stroop test B and MMSE by the Spearman’s Law.　The cut-off value of MCI for dL-Stroop test B was 59.27 seconds, with a sensitivity of 76.73%, specificity of 90.14%.　For the MMSE, the cut-off value was 26/27 points, with a sensitivity of 66.04%, specificity of 88.89%.　Regarding AD, the cut-off value for the dL-Stroop test B was 70.02 seconds, with a sensitivity of 87.30%, specificity of 88.10%.　The MMSE cut-off value was 24/25 points, with a sensitivity of 85.71%, specificity of 77.98%.
CONCLUSION:The range of MCI detection using the dL-Stroop test B was 60-69 seconds, while for the MMSE was 25-26 points.　The dL-Stroop test B is a quick and simple screening tool better than the MMSE for detecting MCI and AD.
Keywords:L-Stroop test, The digital version B of L-Stroop test （dL-Stroop test B）, Mild Cognitive Impairment （MCI）, Alzheimer’s disease （AD）

Address correspondence to Dr. Woon Joo Lee, Osaka Lee Clinic（1-13-15 Honjo-nishi, Kita-ku, Osaka-city, Osaka-fu, Japan 531-0073）