My contribution to dementia research

Hiroyuki Arai

Institute of Development, Aging and Cancer, Tohoku University Division of Brain Sciences Department of Geriatrics and Gerontology

    In my presidential lecture at 28^th Annual meeting of Japan Society for Dementia Research, I would like to address the question of "What have you done in dementia research?  I believe that I have done three major original contributions;no more than this and no less than this.
    1)  Development of cerebrospinal fluid tau as a potential biomarker of Alzheimer's disease.
    2)  Benefits from Yokukansan, a traditional Chinese medicine, as a BPSD-reducing agent.
    3)  Development of BF-227 as an imaging probe of brain amyloid.
    I would like to express special thanks to Prof. Trojanowski JQ and Prof. Lee VMY at The University of Pennsylvania.

Address correspondence to Dr.Hiroyuki Arai, Institute of Development, Aging and Cancer, Tohoku University Division of Brain Sciences Department of Geriatrics and Gerontology(4-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan)