SPECT study of healthy volunteers using the easy Z-score Imaging System (eZIS）

Reiko Miyamoto, M.D.¹⁾, Manabu Kameda, R.T.²⁾, Toshiyuki Ueda, R.T.²⁾, Akira Asano, M.D.³⁾, Akimitsu Saito, M.D.¹⁾, Yoshinori Kawaguchi, M.D.¹⁾

¹⁾Department of Internal Medicine, Nissei Hospital
²⁾Department of Radiology, Hokusei Hospital
³⁾Department of Internal Medicine, Hokusei Hospital

To evaluate the reliability of the easy Z-score Imaging System (eZIS), the eZIS images of 5 healthy volunteers (mean age±SD, 49±13 yrs; range, 26-65 years) were analyzed; 3 of the 5 volunteers were physicians. After confirming that all subjects had no abnormal findings on brain-MRI or CT, eZIS images were obtained using a brain SPECT (E-CAM, Toshiba, Tokyo, Japan). The images showed that all subjects had significant reductions in cerebral blood flow. Furthermore, two subjects had cerebral blood flow reductions in the posterior cingulate gyrus and precuneus, such findings are seen in early-stage Alzheimer's disease. Given these findings, the use of eZIS requires further study.

Address correspondence to Dr. Reiko Miyamoto, Department of Internal Medicine, Nissei Hospital (Akebono 2-2-2, Teine-ku, Sapporo 060-0832, Japan)