Fukushima J. Med. Sci., Vol. 56, No. 1, 2010

[Case Report]

A CASE OF HENOCH-SCHOENLEIN PURPURA NEPHRITIS RECURRING
AFTER 3 YEARS REMISSION

YUMIKO USHIJIMA, YUKIHIKO KAWASAKI, MARIKO KANEKO,
KENTARO HANEDA, NOBUKO SAKAI, KAZUHIDE SUYAMA,
KOICHI HASHIMOTO and MITSUAKI HOSOYA

Department of Pediatrics, Fukushima Medical University School of Medicine,1 Hikariga-oka, Fukushima City, Fukushima, Japan

(Received November 18, 2009, accepted April 14, 2010)

Abstract: Henoch-Schoenlein purpura (HSP) is a systemic disorder characterized by leukocytoclastic vasculitis involving the capillaries with IgA immune complexes deposition, and about 7% of patients with HSP experience recurrence. Most patients with recurring of HSP nephritis show a recurrence of clinical symptoms over a period ranging from 2 to 5 months, even after the disappearance of initial symptoms. Here we report a 9-year-old girl diagnosed with recurrent HSP and severe crescentic glomerulonephritis 3 years after complete resolution of the initial symptoms of HSP. Our case is unique in respect of the recurrence at more than 3 years after the complete resolution of initial symptoms, suggesting that careful follow-up is required in spite of improved renal symptoms in cases of HSP.

Key words: HSPN, Recurrence, Plasmapheresis, Mizoribine Methylprednisolone and urokinase pulse therapy

牛嶋裕美子，川崎幸彦，金子真理子，羽田謙太郎，酒井信子，陶山和秀，橋本浩一，細矢光亮

Corresponding author:Yukihiko Kawasaki
E-mail:kyuki@fmu.ac.jp
http://fmu.ac.jp/lib/F-igaku/
http://www.sasappa.co.jp/online/