Fukushima J. Med. Sci.,
Vol. 52, No. 2, 2006

[Case Report]

A CASE OF RAPIDLY EXPANDING AND INCREASING FOCAL
NODULAR HYPERPLASIA

AI SATO¹⁾, TSUYOSHI RAI²⁾, ATSUSHI TAKAHASHI¹⁾, HIRONOBU SAITO¹⁾,
TADAYUKI TAKAGI¹⁾, GORO SHIBUKAWA¹⁾, TAKERU WAKATSUKI¹⁾,
YUTA TAKAHASHI¹⁾, ATSUSHI IRISAWA¹⁾, KAZUYA ISE³⁾,
KAZUO WATANABE⁴⁾, MITSUKAZU GOTOH³⁾
and HIROMASA OHIRA¹⁾

¹⁾Department of Internal Medicine II, Fukushima Medical University School
of Medicine, Fukushima, 960-1295, Japan
²⁾Miharu Hospital, Fukushima, 963-7752, Japan
³⁾Department of Surgery I, Fukushima Medical University School of Medicine,
Fukushima, 960-1295, Japan
⁴⁾Department of Pathology II, Fukushima Medical University School of Medicine,
Fukushima, 960-1295, Japan

(Received June 28, 2006, accepted July 11, 2006)

Abstract: We report a case of 14-year-old male patient who underwent bile-duct-to-jejunum anastomosis because of congenital biliary atresia at the age of 2 months. A 15 mm hypervascular nodule was detected for the first time in the S1 region of the liver at the age of 9 years. Two years later, 6 hypervascular nodules were found in the liver. A tumor biopsy was performed. It was diagnosed as a focal nodular hyperplasia (FNH). However, the number of nodules increased from 6 to 12 and those diameters were enlarged two to seven times one year later; the tumor biopsy was performed again. Histologically, the findings were consistent with those obtained previously, which indicated FNH. We consider that this is a very rare case of FNH in which both the number of nodules and the size were increased in a short period of time. We present it here as a valuable case report.

Key words: Congenital biliary atresia, cirrhosis, FNH

佐藤　愛，雷　　毅，高橋敦史，斎藤広信，高木忠之，渋川悟朗，若槻　尊，高橋裕太，入澤篤志，伊勢一哉，渡邉一男，後藤満一，大平弘正

Correspondence to: Ai Sato, Department of Internal Medicine II, Fukushima Medical University School of Medicine, Fukushima City 960-1295, Japan
E-mail: a-satoh@fmu.ac.jp