Fukushima J. Med. Sci.,
Vol. 50, No. 1, 2004

［Case Report］

POLYMYOSITIS ASSOCIATED WITH URINARY BLADDER CANCER :
AN AUTOPSY CASE

ISAO TAKEDA¹⁾, KOTA SUGISAKI¹⁾, HARUYO IWADATE¹⁾,
TAKASHI KANNO¹⁾, HAJIME ODAJIMA²⁾, KATSUHITO KAMIMURA²⁾,
HIDEO SAKUMA²⁾, HITOSHI ENDO³⁾ and REIJI KASUKAWA¹⁾

Divisions of ¹⁾Rheumatology and
²⁾Clinical Pathology, Ohta Nishinouchi Hospital, Koriyama
³⁾Division of Orthopedic Surgery, Tsuboi Hospital, Koriyama

(Received February 25, 2004, accepted March 25, 2004)

Abstract: A 56-year-old man suffered from muscle weakness with elevated serum creatine kinase.　Under diagnosis of polymyositis, the patient was treated with corticosteroid, methotrexate and cyclosporin A.　Eleven months after the first signs of muscle weakness, the patient suffered an abrupt onset of anuria and underwent hemodialysis.　The patient died of respiratory insufficiency 14 months after the first signs of muscle weakness.
      Autopsy findings revealed associated urinary bladder cancer with histological indications of adenosquamous cell carcinoma, liver metastasis and cancerous lymphangitis of the lung.

Key words: polymyositis, urinary bladder cancer, interstitial lung disease, anuria, cyclosporin A

武田　功，杉崎康太，岩舘治代，菅野　孝，小田島肇，上村勝人，佐久間秀夫，遠藤　仁，粕川禮司

Correspondence to: Reiji Kasukawa, Division of Rheumatology, Ohta Nishinouchi Hospital, 2-5-20 Nishinouchi, Koriyama City 963-8558, Japan.